Lymphatic filariasis
30 January 2020 | Q&ALymphatic filariasis is a parasitic disease caused by three species of microscopic, thread-like worms. The adult worms only live in the human lymph system. The lymph system maintains the body's fluid balance and fights infections.
Lymphatic filariasis, considered globally as a neglected tropical disease (NTD), is a parasitic disease caused by microscopic, thread-like worms. The adult worms only live in the human lymph system. The lymph system maintains the body’s fluid balance and fights infections. Lymphatic filariasis is spread from person to person by mosquitoes.
People with the disease can suffer from lymphedema and elephantiasis and in men, swelling of the scrotum, called hydrocele. Lymphatic filariasis is a leading cause of permanent disability worldwide. Communities frequently shun and reject women and men disfigured by the disease. Affected people frequently are unable to work because of their disability, and this harms their families and their communities.
Lymphatic filariasis is caused by infection with parasites classified as nematodes (roundworms) of the family Filariodidea. There are 3 types of these thread-like filarial worms: Wuchereria bancrofti, which is responsible for 90% of the cases. Brugia malayi, which causes most of the remainder of the cases.
Since there is no known vaccine or cure for lymphatic filariasis, the most effective method that exists to control the disease is prevention. ... In addition to drug treatments, there are other preventative methods.
Best treatment.
During Mass drug administration campaign, the drug Diethylcarbamazine (DEC) is administrated to population. It kills the microfilariae and some of the adult worms. DEC has been used world-wide for more than 50 years.
The standard method for diagnosing active infection is the identification of microfilariae in a blood smear by microscopic examination. The microfilariae that cause lymphatic filariasis circulate in the blood at night (called nocturnal periodicity).
Signs and symptoms
- Fever.
- Inguinal or axillary lymphadenopathy.
- Testicular and/or inguinal pain.
- Skin exfoliation.
- Limb or genital swelling - Repeated episodes of inflammation and lymphedema lead to lymphatic damage, chronic swelling, and elephantiasis of the legs, arms, scrotum, vulva, and breasts.
Lymphatic filariasis affects over 120 million people in 72 countries throughout the tropics and sub-tropics of Asia, Africa, the Western Pacific, and parts of the Caribbean and South America.